| Black Cohosh |
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| Botanical Name: |
Actaea racemosa L, Cimicifuga
racemosa |
| Common Names: |
Black Snakeroot, Bugbane, Bugwort,
Rattle Weed, Squawroot |
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| Overview |
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More than two centuries ago, Native Americans discovered that
the root of the black cohosh plant (Cimicifuga racemosa)
helped relieve menstrual cramps, and symptoms of menopause
including hot flashes, irritability, mood swings, and sleep
disturbances. Today, the roots of black cohosh are still often
used for these purposes. In fact, the herb has been widely used
for more than 40 years in Europe and is approved in Germany for
premenstrual discomfort, painful menstruation, and menopausal
symptoms.
Menopausal Symptoms
A dozen studies or more conducted throughout the 1980s and 1990s
confirm that the long-standing use of black cohosh for
menopausal symptoms has scientific validity. For example, in a
German study involving 629 women, black cohosh improved physical
and psychological menopausal symptoms in more than 80% of the
participants within four weeks. In a second study, 60 menopausal
women were given black cohosh extract, conjugated estrogens, or
diazepam (a leading anti-anxiety medication) for three months.
Those who received black cohosh reported feeling significantly
less depressed and anxious than those who received either
estrogens or diazepam. In another study, 80 menopausal women
were treated for 12 weeks with black cohosh extract, conjugated
estrogens, or placebo. Black cohosh improved anxiety, menopause
and vaginal symptoms. In addition, the number of hot flashes
dropped from 5 to less than 1 average daily occurences in the
black cohosh group compared to those taking estrogen in whom hot
flashes dropped from 5 to 3.5 daily occurences.
Given these examples, and results of other studies, some
experts have concluded that black cohosh may be a safe and
effective alternative to estrogen replacement therapy (ERT) for
women who cannot or will not take ERT for menopause.
The American College of Obstetricians and Gynecologists (ACOG)
reports, however, that many of these studies were poorly
designed and did not evaluate the safety and effectiveness of
black cohosh beyond 6 months of use. Despite this limited
evidence, the ACOG still recognizes the value of black cohosh
for menopausal symptoms. Until further studies are conducted,
however, the ACOG recommends only short-term (less than 6
months) use of this herb for the relief of hot flashes
specifically.
Hot Flashes with treatment for Breast Cancer
Many breast cancer patients use black cohosh to ease hot
flashes, a common side effect of medications used to treat
breast cancer such as tamoxifen. While black cohosh may reduce
the number and intensity of hot flashes in breast cancer
patients, two well-designed studies recently concluded that the
herb is no more effective than placebo.
In addition, although there is some debate about this, black
cohosh may contain plant based estrogens, called phytoestrogens.
Therefore, there is some concern that if there are
phytoestrogens in black cohosh, they may stimulate the growth of
breast tumors. This idea has not been substantiated
scientifically; in fact, some studies suggest that black cohosh
may inhibit the growth of breast cancer cells in test tubes.
Additional research is needed before conclusions can be drawn
about use of black cohosh in women with a history of or risk for
developing breast cancer (such as strong family history).
Arthritis
Preliminary studies also suggest that black cohosh may help
reduce inflammation associated osteoarthritis and rheumatoid
arthritis. In a review of scientific studies, researchers
concluded that a combination of black cohosh, willow bark (Salix
spp.), sarsaparilla (Smilax spp.), guaiacum (Guaiacum
officinale) resin, and poplar bark (Populus tremuloides)
may help relieve symptoms of osteoarthritis.
Osteoporosis
Some experts suggest that the plant based estrogens in black
cohosh, in theory, could help prevent osteoporosis. This theory
has yet to be tested scientifically.
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| Plant Description |
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Black cohosh is a tall, flowering plant found in rich, shady
woods in eastern areas of North America. A member of the
buttercup family, black cohosh is also known as black snakeroot,
bugbane, bugwort, and squawroot. Its rhizomes and roots (both
underground parts of the plant) are used for medicinal purposes.
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| What's It Made Of? |
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Black cohosh contains glycosides (sugar compounds),
isoferulic acids (substances with anti-inflammatory effects),
and, possibly, phytoestrogens (plant based estrogens), among
several other active substances.
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| Available Forms |
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Black cohosh is available in capsules, tablets, liquid
tincture that can be mixed in water, and dried root that can be
simmered in water.
Black cohosh should not be confused with blue cohosh, an herb
that is reported to have similar effects, but has not been
thoroughly tested for its safety and effectiveness and may
actually behave like nicotine.
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| How to Take It |
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Pediatric
There are no known scientific reports on the pediatric use of
black cohosh. Therefore, it is not currently recommended for
children.
Adult
The recommended dose of black cohosh ranges from 40 to 80 mg
per day. For black cohosh tincture, that equals 2 to 4 mL, three
times per day in water or tea. Capsules or tablets may be
preferred; two will likely provide the recommended daily dose.
To make a black cohosh drink, put 20 g of dried root in 34 oz
of water. Bring to a boil and then simmer 20 to 30 minutes until
the liquid is reduced by a third. Strain, cover, and store in
the refrigerator or a cool, dry place. The liquid keeps for up
to 48 hours. Drink one cup three times daily.
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| Precautions |
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The use of herbs is a time-honored approach to strengthening
the body and treating disease. Herbs, however, contain active
substances that can trigger side effects and that can interact
with other herbs, supplements, or medications. For these
reasons, herbs should be taken with care, under the supervision
of a practitioner knowledgeable in the field of botanical
medicine.
Some individuals taking high doses of black cohosh have
reported side effects including abdominal pain, diarrhea,
dizziness, headaches, joint pains, nausea, slow heart rate,
tremors, visual dimness, and vomiting.
It is not clear at this point whether black cohosh stimulates
the growth of breast cancer cells or inhibits their growth;
research to date has been limited and has produced mixed
results. Women with a history of breast cancer, therefore, and
those at a high risk for developing breast cancer (for example,
a strong family history like a mother or sister with breast
cancer) should not take black cohosh without talking to a
healthcare provider.
Pregnant and breastfeeding women should avoid black cohosh as
the herb may stimulate contractions and lead to premature labor.
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| Possible Interactions |
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There are no known scientific reports of interactions between
black cohosh and conventional medications.
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| Supporting Research |
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Blumenthal M, Busse WR, Goldberg A, et al. The Complete
German Commission E Monographs: Therapeutic Guide to Herbal
Medicines. Boston, Mass: Integrative Medicine
Communications; 19998:90.
Blumenthal M, Goldberg A, Brinkmann J, eds. Herbal
Medicine: Expanded Commission E Monographs. Newton, Mass:
Integrative Medicine Communications; 2000:22-26.
Dixon-Shanies D, Shaikh N. Growth inhibition of human breast
cancer cells by herbs and phytoestrogens. Oncol Rep.
1996;6(6):1383-1387.
Ernst E, Chrubasik S. Phyto–anti-inflammatories. A
systematic review of randomized, placebo-controlled,
double-blind trials. Rheum Dis Clin North Am.
2000;26(1):13-27.
Foster S. Black Cohosh: Cimicifuga racemosa. A
literature review. HerbalGram. 1999;45:37-49.
Foster S, Tyler V. Tyler's Honest Herbal. Binghamton,
NY: The Haworth Herbal Press; 2000.
Guillaume G. Postmenopausal osteoporosis and Chinese
medicine. Am J Acupuncture. 1992;20(2):105-111.
Jacobson JS, Troxel AB, Evans J, et al. Randomized trial of
black cohosh for the treatment of hot flashes among women with a
history of breast cancer. J Clin Oncol.
2001;19(10):2739-2745.
Lieberman S. A review of the effectiveness of Cimicifuga
racemosa (black cohosh) for the symptoms of menopause. J
Womens Health. 1998;5:525–529.
Liske E. Therapeutic efficacy and safety of Cimicifuga
racemosa for gynecologic disorders. Advances in Natural
Therapy. 1998;75:45-53.
McFarlin BL, Gibson MH, O'Rear J, et al. A national survey of
herbal preparation use by nurse-midwives for labor stimulation.
Review of the literature and recommendations for practice. J
Nurse Midwifery. 1999;44(3):205–216.
McKenna DJ, Jones K, Humphrey S, Hughes K. Black cohosh:
efficacy, safety, and use in clinical and preclinical
applications. [Review]. Altern Ther Health Med.
2001;7(3):93-100.
Pepping J. Alternative therapies: black cohosh: Cimicifuga
racemosa. Am J Health-Syst Pharm. 1999;56:1400-1402.
Rotblatt M, Ziment I. Evidence-based herbal medicine.
Philadelphia, PA: Hanley & Belfus, Inc.;2002:98-103.
Schulz V, Hänsel R, Tyler VE. Rational Phytotherapy.
Berlin, Germany: Springer-Verlag; 1998.
Taylor M. Alternatives to Hormone Replacement Therapy.
Comprehensive Therapy. 1997;23:514–532.
Thacker HL, Booher DL. Management of perimenopause: focus on
alternative therapies. Cleveland Clin J Med.
1999;66(40):213–218.
Wade C, Kronenberg F, Kelly A, Murphy PA. Hormone-modulating
herbs: implications for women's health. J Am Med Womens Assoc.
1999;54(4):181-183.
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| Review Date: April
2002 |
Reviewed By: Participants
in the review process include: Constance Grauds (April 1999),
RPh, President, Association of Natural Medicine Pharmacists, San
Rafael, CA; Jacqueline A. Hart, MD, Department of Internal
Medicine, Newton-Wellesley Hospital, Harvard University and
Senior Medical Editor Integrative Medicine, Boston, MA; Gary
Kracoff, RPh (Pediatric Dosing section February 2001), Johnson
Drugs, Natick, MA; Steven Ottariono, RPh (Pediatric Dosing
section February 2001), Veteran's Administrative Hospital,
Londonderry, NH; R. Lynn Shumake, PD, Director, Alternative
Medicine Apothecary, Blue Mountain Apothecary & Healing
Arts, University of Maryland Medical Center, Glenwood, MD; Tom
Wolfe, P.AHG (April 1999), Smile Herb Shop, College Park, MD.
All interaction sections have also been reviewed by a team of
experts including Joseph Lamb, MD (July 2000), The Integrative
Medicine Works, Alexandria, VA;Enrico Liva, ND, RPh (August
2000), Vital Nutrients, Middletown, CT; Brian T Sanderoff, PD,
BS in Pharmacy (March 2000), Clinical Assistant Professor,
University of Maryland School of Pharmacy; President, Your
Prescription for Health, Owings Mills, MD; Ira Zunin, MD, MPH,
MBA (July 2000), President and Chairman, Hawaii State Consortium
for Integrative Medicine, Honolulu, HI.
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Copyright © 2004 A.D.A.M., Inc
The publisher does not accept any
responsibility for the accuracy of the information or the
consequences arising from the application, use, or misuse of any
of the information contained herein, including any injury and/or
damage to any person or property as a matter of product
liability, negligence, or otherwise. No warranty, expressed or
implied, is made in regard to the contents of this material. No
claims or endorsements are made for any drugs or compounds
currently marketed or in investigative use. This material is not
intended as a guide to self-medication. The reader is advised to
discuss the information provided here with a doctor, pharmacist,
nurse, or other authorized healthcare practitioner and to check
product information (including package inserts) regarding
dosage, precautions, warnings, interactions, and
contraindications before administering any drug, herb, or
supplement discussed herein.
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